SNDX SEC Filing News — Syndax Pharmaceuticals, Inc.

Latest SEC filings for Syndax Pharmaceuticals, Inc. (SNDX) explained in plain English. Covers insider buying and selling (Form 4), proposed insider sales (Form 144), material company events (8-K), and quarterly & annual reports (10-Q / 10-K). StrongBuyAnalytics provides navigation and brief excerpts or summaries; original filings remain at the SEC/source links and were authored by their filers, not StrongBuyAnalytics. Filing dates shown are source dates. Coverage and detection can be delayed or incomplete because of SEC availability, amendments, parsing, caching, or outages. Latest source filing date shown: 2026-08-04.

Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory R/R acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. The company is also developing revumenib for the treatment of R/R acute myeloid leukemia (AML) with a n…
Sector: Healthcare Industry: Biotechnology Market Cap: $1.2B
20
Total Filings
0
Bullish Classifications
5
Bearish Classifications
5
Insider Transactions
7
Material Events (8-K)
3
Periodic Reports
Rule-based classifications for SNDX currently lean bearish. Of the 20 filing records displayed, 5 carry bearish classifications (such as insider sales or negative 8-K disclosures) versus 0 bullish. This does not necessarily signal fundamental deterioration — insiders sell for many reasons — but it is worth monitoring alongside the company's core financial metrics.
SNDX Filing Activity Snapshot 2026-02-10 — 2026-08-04
Insider Transactions (Form 4)
0 buys vs 5 sells
Net insider selling in this period — insiders sell for many reasons beyond conviction.
Largest Form 144 Filing
$1.18M
Botwood Nicholas A.J. (Head of R&D, CMO) · 2026-06-12
65,515 shares · Form 4
Form 144 Notices
5
Proposed insider sales filed — Form 144 is a notice of intent, not a confirmed transaction. Actual sales are confirmed via Form 4.
Insider Transactions 5 · Forms 3, 4 and 5

A Form 4 is filed within two business days of a company insider — an officer, a director, or a holder of more than ten percent of the stock — changing their position in the shares. All 5 filings in this group are Form 4s for Syndax Pharmaceuticals, Inc.

The difficulty with reading these filings as a group is that a single form type covers transactions that mean entirely different things. An executive spending their own money to buy stock and an executive having shares withheld to pay tax on a vesting grant both appear as a Form 4. Every filing below is therefore tagged with the nature of the underlying transaction, taken from the transaction code reported on the form itself.

Across the 5 insider filings shown, the breakdown is 5 open-market sale. 5 of them involved a discretionary open-market trade; the rest are compensation and administrative mechanics.

What each transaction type means

Open-market sale ×5
The insider sold shares on the open market. Sales may be discretionary or executed automatically under a pre-arranged Rule 10b5-1 trading plan, and a Form 4 does not always make clear which applies.
Form 4 Open-market sale Insider Selling 2026-07-09

SNDX insider Metzger Michael A (Director, Chief Executive Officer) sold 32,375 shares (~$784.8K)

Metzger Michael A, listed as Director, Chief Executive Officer at Syndax Pharmaceuticals Inc, reported an open-market sale of 32,375 SNDX shares in a Form 4 filing. This is a confirmed insider sale, not just a proposed sale notice.

The insider sold shares on the open market. Sales may be discretionary or executed automatically under a pre-arranged Rule 10b5-1 trading plan, and a Form 4 does not always make clear which applies.

Transactions reported on this filing
Code Nature Shares Price Value
M Option exercise 32,375 $6.38 $206.6K
S Open-market sale 32,375 $24.24 $784.8K
M Option exercise derivative · Stock Option (Right to buy) 32,375 — —
Filing: Form 4 (Insider Transaction) Insider: Metzger Michael A (Director, Chief Executive Officer) Shares: 32,375 Est. Value: $784.8K
Form 4 Open-market sale Insider Selling 2026-06-12

SNDX insider Botwood Nicholas A.J. (Head of R&D, CMO) sold 65,515 shares (~$1.18M)

Botwood Nicholas A.J., listed as Head of R&D, CMO at Syndax Pharmaceuticals Inc, reported an open-market sale of 65,515 SNDX shares in a Form 4 filing. This is a confirmed insider sale, not just a proposed sale notice.

The insider sold shares on the open market. Sales may be discretionary or executed automatically under a pre-arranged Rule 10b5-1 trading plan, and a Form 4 does not always make clear which applies.

Transactions reported on this filing
Code Nature Shares Price Value
M Option exercise 22,515 $13.82 $311.2K
S Open-market sale 34,280 $18.00 $617.0K
M Option exercise 31,235 $13.82 $431.7K
S Open-market sale 31,235 $18.14 $566.6K
M Option exercise derivative · Stock options (Right to buy) 22,515 — —
M Option exercise derivative · Stock options (Right to buy) 31,235 — —
Filing: Form 4 (Insider Transaction) Insider: Botwood Nicholas A.J. (Head of R&D, CMO) Shares: 65,515 Est. Value: $1.18M
Form 4 Open-market sale Insider Selling 2026-06-02

SNDX insider Goldan Keith A. (Chief Financial Officer) sold 1,177 shares (~$22.4K)

Goldan Keith A., listed as Chief Financial Officer at Syndax Pharmaceuticals Inc, reported an open-market sale of 1,177 SNDX shares in a Form 4 filing. This is a confirmed insider sale, not just a proposed sale notice.

The insider sold shares on the open market. Sales may be discretionary or executed automatically under a pre-arranged Rule 10b5-1 trading plan, and a Form 4 does not always make clear which applies.

Transactions reported on this filing
Code Nature Shares Price Value
S Open-market sale 1,177 $18.99 $22.4K
Filing: Form 4 (Insider Transaction) Insider: Goldan Keith A. (Chief Financial Officer) Shares: 1,177 Est. Value: $22.4K
Form 4 Open-market sale Insider Selling 2026-06-02

SNDX insider Metzger Michael A (Director, Chief Executive Officer) sold 6,847 shares (~$130.0K)

Metzger Michael A, listed as Director, Chief Executive Officer at Syndax Pharmaceuticals Inc, reported an open-market sale of 6,847 SNDX shares in a Form 4 filing. This is a confirmed insider sale, not just a proposed sale notice.

The insider sold shares on the open market. Sales may be discretionary or executed automatically under a pre-arranged Rule 10b5-1 trading plan, and a Form 4 does not always make clear which applies.

Transactions reported on this filing
Code Nature Shares Price Value
S Open-market sale 6,847 $18.99 $130.0K
Filing: Form 4 (Insider Transaction) Insider: Metzger Michael A (Director, Chief Executive Officer) Shares: 6,847 Est. Value: $130.0K
Form 4 Open-market sale Insider Selling 2026-02-10

SNDX insider Metzger Michael A (Director, Chief Executive Officer) sold 17,159 shares (~$360.8K)

Metzger Michael A, listed as Director, Chief Executive Officer at Syndax Pharmaceuticals Inc, reported an open-market sale of 17,159 SNDX shares in a Form 4 filing. This is a confirmed insider sale, not just a proposed sale notice.

The insider sold shares on the open market. Sales may be discretionary or executed automatically under a pre-arranged Rule 10b5-1 trading plan, and a Form 4 does not always make clear which applies.

Transactions reported on this filing
Code Nature Shares Price Value
S Open-market sale 17,159 $21.03 $360.8K
Filing: Form 4 (Insider Transaction) Insider: Metzger Michael A (Director, Chief Executive Officer) Shares: 17,159 Est. Value: $360.8K
Proposed Insider Sales 5 · Form 144

A Form 144 is a notice of intent to sell restricted or control securities. It is not a record that anything was sold. Syndax Pharmaceuticals, Inc. has 5 such notices in this period.

The distinction matters because a Form 144 is frequently reported as though it were a completed insider sale. The filer may sell all of the shares covered, some of them, or none at all, and there is no obligation to update the notice either way. A sale that is actually executed by an officer or director shows up separately on a Form 4, which is the filing to check before treating a proposed sale as a real one.

Form 144 Proposed Insider Sale 2026-07-08

SNDX Form 144 filed for proposed insider sale by MICHAEL METZGER (32,375 shares) ~$752.4K

MICHAEL METZGER filed a Form 144 with the SEC indicating intent to sell SNDX (Syndax Pharmaceuticals Inc) shares. Form 144 reflects a proposed sale, not a completed transaction. The actual execution, if any, would typically appear later in a Form 4.

Filing: Form 144 (Proposed Sale Notice) Insider: MICHAEL METZGER Shares: 32,375 Est. Value: $752.4K
Form 144 Proposed Insider Sale 2026-06-12

SNDX Form 144 filed for proposed insider sale by Botwood Nicholas A.J. (31,235 shares) ~$566.7K

Botwood Nicholas A.J. filed a Form 144 with the SEC indicating intent to sell SNDX (Syndax Pharmaceuticals Inc) shares. Form 144 reflects a proposed sale, not a completed transaction. The actual execution, if any, would typically appear later in a Form 4.

Filing: Form 144 (Proposed Sale Notice) Insider: Botwood Nicholas A.J. Shares: 31,235 Est. Value: $566.7K
Form 144 Proposed Insider Sale 2026-06-11

SNDX Form 144 filed for proposed insider sale by Botwood Nicholas A.J. (34,280 shares) ~$609.4K

Botwood Nicholas A.J. filed a Form 144 with the SEC indicating intent to sell SNDX (Syndax Pharmaceuticals Inc) shares. Form 144 reflects a proposed sale, not a completed transaction. The actual execution, if any, would typically appear later in a Form 4.

Filing: Form 144 (Proposed Sale Notice) Insider: Botwood Nicholas A.J. Shares: 34,280 Est. Value: $609.4K
Form 144 Proposed Insider Sale 2026-06-01

SNDX Form 144 filed for proposed insider sale by Goldan Keith A. (1,177 shares) ~$22.4K

Goldan Keith A. filed a Form 144 with the SEC indicating intent to sell SNDX (Syndax Pharmaceuticals Inc) shares. Form 144 reflects a proposed sale, not a completed transaction. The actual execution, if any, would typically appear later in a Form 4.

Filing: Form 144 (Proposed Sale Notice) Insider: Goldan Keith A. Shares: 1,177 Est. Value: $22.4K
Form 144 Proposed Insider Sale 2026-06-01

SNDX Form 144 filed for proposed insider sale by Metzger Michael A (6,847 shares) ~$130.0K

Metzger Michael A filed a Form 144 with the SEC indicating intent to sell SNDX (Syndax Pharmaceuticals Inc) shares. Form 144 reflects a proposed sale, not a completed transaction. The actual execution, if any, would typically appear later in a Form 4.

Filing: Form 144 (Proposed Sale Notice) Insider: Metzger Michael A Shares: 6,847 Est. Value: $130.0K
Material Events 7 · Form 8-K

An 8-K reports a material event in the window between scheduled reports. There are 7 in this period for Syndax Pharmaceuticals, Inc. Each 8-K names the item number it is filed under, and that number is the fastest way to tell a routine disclosure from a consequential one.

Item 2.02 is an earnings release, Item 5.02 is a change of directors or officers, and Item 1.01 or 2.01 covers a material agreement or a completed acquisition. Item 7.01 and Item 8.01 are the general-purpose disclosure items and carry no fixed meaning on their own.

Form 8-K Material Company Update 2026-08-04

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Form 8-K Material Company Update 2026-07-14

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Form 8-K Material Company Update 2026-06-10

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Form 8-K Material Company Update 2026-06-10

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Form 8-K Material Company Update 2026-06-04

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Form 8-K Material Company Update 2026-04-30

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Form 8-K Material Company Update 2026-02-26

SNDX filed 8-K — material company event

Syndax Pharmaceuticals Inc filed an 8-K with the SEC reporting a material event. Summary unavailable — view the original SEC filing for the full text.

Filing: 8-K (Material Event)
Periodic Reports 3 · Forms 10-K and 10-Q

The periodic reports are where the audited and reviewed financial statements live. This period contains 1 annual report (10-K) and 2 quarterly reports (10-Q) for Syndax Pharmaceuticals, Inc.

The two are not equivalent in weight. A 10-K is audited by an external firm and includes the full risk factor disclosure, business description and management discussion; a 10-Q is unaudited, reviewed rather than examined, and much shorter. When a figure in a quarterly report is later revised, the annual report is usually where the correction appears.

An amended report — 10-K/A or 10-Q/A — restates or corrects something in the original filing, and is worth reading against the version it replaces.

Form 10-Q Quarterly Report 2026-08-04

SNDX filed Quarterly Report (10-Q)

Syndax Pharmaceuticals Inc filed its quarterly report with the SEC. This report includes unaudited financial statements and management discussion for the quarter.

Filing: 10-Q (Quarterly Report)
Form 10-Q Quarterly Report 2026-04-30

SNDX filed Quarterly Report (10-Q)

Syndax Pharmaceuticals Inc filed its quarterly report with the SEC. This report includes unaudited financial statements and management discussion for the quarter.

Filing: 10-Q (Quarterly Report)
Form 10-K Annual Report 2026-02-26

SNDX filed Annual Report (10-K)

Syndax Pharmaceuticals Inc filed its annual report with the SEC. This report includes audited financial statements, business overview, risk factors, and management discussion.

Filing: 10-K (Annual Report)

How we classify Syndax Pharmaceuticals, Inc.'s filings

Straight from EDGAR

Each displayed record links to an original source document. StrongBuyAnalytics provides navigation and brief excerpts or summaries, not the filing itself. Parsing may omit context or contain errors, so read the original document in full.

Transaction codes, not guesswork

The nature shown on each insider filing comes from the transaction code the filer entered on the form itself — P for an open-market purchase, A for a compensation award, F for shares withheld to pay tax, M for an option exercise. Where one filing contains several codes, the transaction table lists them line by line.

Why the distinction matters

Insider activity is routinely summarised as buying or selling, which flattens together decisions that mean very different things. Shares withheld for tax on a vesting grant are an automatic administrative step; shares bought on the open market are someone committing their own money at the current price.

What this page does not tell you

A filing records what happened, not why. Form 4 does not always disclose whether a sale was executed under a pre-arranged Rule 10b5-1 plan, and no single filing is a basis for a decision on SNDX. Read these alongside the fundamentals rather than in isolation.

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Publisher, sources & limitations — September 15, 2026. StrongBuyAnalytics provides navigation and brief excerpts or summaries for educational use. Original filings remain at SEC EDGAR or other displayed source links; StrongBuyAnalytics does not author them. Filing dates are source dates, not publication dates for this page. Coverage can be delayed, incomplete, amended, or unavailable because of SEC/source availability, parsing, caching, or outages. Verify every material statement in the original filing.
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