PYXS Fundamental Analysis & Score

Pyxis Oncology, Inc. Healthcare Biotechnology
$1.68
Quote dated October 16, 2026
39/100
Caution

What this score covers. It is a fixed screen of five reported ratios with no valuation input, so a company can score highly while its valuation risk remains elevated. The full report scores valuation separately, as one of nine scored sections. How the score is calculated

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Page generated: October 18, 2026 at 20:53 UTC

Key Financial Metrics

Market Cap
$200.69M
Gross Margin
78.4%
Net Margin
0.0%
Return on Equity
-179.1%
Debt/Equity
1.56

Rule-Based Financial Screen Summary

Pyxis Oncology, Inc. (PYXS) is a Healthcare company in the Biotechnology industry. It has a 39/100 Caution score on our five-factor fundamentals screen. Key strengths include Gross Margin (78.4%). Areas to watch: Net Margin (0.0%), Return on Equity (-179.1%). The score is a five-factor screen — revenue growth, gross margin, net margin, return on equity and debt-to-equity — each scored against fixed thresholds from a neutral starting point of 50 points. The full report scores nine sections, including moat, free cash flow, dilution and valuation, which this screen does not.

Gross Margin: Excellent Net Margin: Negative Return on Equity: Negative Debt/Equity: High Risk

This page score and the strengths and concerns above are produced by deterministic, rule-based calculations from the available third-party financial inputs documented below. AI does not choose the score, strengths, or concerns. Data and automated summaries can contain errors. This is not personalized investment advice. See our methodology and disclaimer.

How this page score was calculated

The calculation starts at 50 points and applies the five fixed adjustments shown below. Missing or invalid inputs contribute no adjustment. A finite provider-reported zero is treated as a measured value and evaluated against that input's displayed threshold. The pre-clamp result is 39; the published result is clamped to a minimum of 10 and maximum of 98, producing 39/100.

PYXS score inputs and fixed adjustments
Input Displayed value Threshold applied Adjustment Data status
Revenue Growth Not available No threshold applied +0 Missing — contributes zero
Gross Margin 78.4% > 50% +10 Available
Net Margin 0.0% 0% or lower -8 Available
Return on Equity -179.1% 0% or lower -5 Available
Debt/Equity 1.56 1.00 or higher -8 Available

Score bands

80 or higher: Strong Buy; 65–79: Buy; 50–64: Hold; below 50: Caution.

These are fixed names for score ranges. The score is not a success probability, recommendation, or forecast, and 80/100 does not mean an 80% chance of a gain.

Not included in this score

  • Peer results or relative peer ranking
  • Demand zones or liquidity
  • Technical momentum
  • News or market sentiment
  • DCF valuation or the downloadable report score

Sources, freshness, and limitations

This page was generated . The provider identifies the latest underlying financial period as June 30, 2026. The displayed market quote is dated October 16, 2026. Generation time is not the same as the date of the underlying filing or market observation.

Financial inputs may be delayed, restated, differently standardized by the data provider, or unavailable. Missing, invalid, or non-finite values receive no positive or negative adjustment rather than being estimated. A finite provider-reported zero is retained and evaluated against that metric's displayed threshold; it is not treated as missing. This can make a sparse-data score less informative. The screen does not capture every business, market, valuation, or portfolio risk, and investors can lose money.

What the full PYXS report adds

The 39/100 on this page comes from a fixed screen of 5 ratios. The downloadable report is a separate analysis with its own score, built from 9 weighted sections.

This page: fixed screen

  • Revenue Growth
  • Gross Margin
  • Net Margin
  • Return on Equity
  • Debt/Equity

Each factor is scored against fixed thresholds from a starting point of 50 points. No factor prices the stock, so valuation is not part of the 39/100.

Full report: 9 scored sections

  1. Business Moat weight 15 of 100
  2. Revenue Growth Consistency weight 14 of 100
  3. Margin Quality weight 12 of 100
  4. Free Cash Flow Strength weight 12 of 100
  5. Balance Sheet Safety weight 12 of 100
  6. Returns on Capital weight 12 of 100
  7. Dilution vs Self-Funded Growth weight 8 of 100
  8. Valuation vs Growth weight 10 of 100
  9. Structural vs Cyclical Growth weight 5 of 100

When the inputs allow, the report also shows a fair-value estimate with its discounted cash flow (DCF) assumptions and a 3×3 sensitivity table, a confidence figure, and the data limitations that reduced that confidence. Its headline label can add a valuation-risk flag next to the fundamental-quality rating.

Open the PYXS report page

Supplementary Metrics for PYXS

2 data points drawn from analyst targets, consensus estimates, and ownership data. These are supplementary observations, not event predictions or causal explanations:

The provider-reported analyst mean target is $8.67 (+415.9% from the displayed price), based on 9 estimates. This is third-party opinion, not a StrongBuyAnalytics target.
The provider-reported third-party analyst consensus category is Strong Buy; it is not a StrongBuyAnalytics recommendation.

Risk Indicators for PYXS

6 measurable indicators visible in Pyxis Oncology, Inc.'s reported numbers. These are market and valuation risk metrics — not a comprehensive list of business risks, which would require qualitative analysis beyond this data:

Net Margin (0.0%)
Return on Equity (-179.1%)
Debt/Equity (1.56)
The provider-reported beta is 1.38. A beta above 1 reflects larger historical price moves relative to the provider's benchmark, but it does not predict future volatility or drawdowns.
The provider-reported short ratio is 4.0 days to cover. Short-interest data can be delayed and may reflect hedging or other strategies, so it does not establish investor intent or future direction.
The reported debt-to-equity ratio is above 1. Higher leverage can increase sensitivity to weaker cash flow or higher borrowing costs, but the ratio requires company and industry context.

PYXS Balance Sheet & Cash Flow

Pyxis Oncology, Inc.'s liquidity and cash generation as of the most recent filing — note the cash position of $33.00M against $17.83M of debt:

Total Cash
$33.00M
Total Debt
$17.83M
Current Ratio
1.34
FCF Yield
-11.6%
EBITDA
$-85,526,000
Operating Margin
-812.7%

These are provider-normalized figures and may differ from the issuer's as-filed presentation, units, or latest amendment. Use source filings for verification.

PYXS Valuation Snapshot

Price / Book
9.3x
High intangible value
Analyst Target (Mean)
$8.67
Range: $6 – $19
Dividend Yield
0.00%
52-Week Price Range — PYXS is trading at 14% of its range
$1.03 (52W Low) $5.55 (52W High)

Who Holds PYXS? — Institutional 13F Filings

Institutional investment managers with >$100 M in qualifying assets must disclose their equity positions quarterly on SEC Form 13F — typically within 45 days of quarter-end. Search those filings below to see which hedge funds, mutual funds, and asset managers reported PYXS as a holding, how many shares they held, and how positions changed quarter over quarter.

Search 13F Filings for PYXS Free · no sign-in required · live SEC EDGAR data
What you see free
Which institutions reported PYXS, share counts, reported values, and direct links to the SEC filing.
Research Pro adds
Full manager portfolios — every position a fund holds, quarter-over-quarter changes, and concentration weights.
Data limitation
13F reports covered long positions for the filing's stated reporting period, typically a quarter-end—not on its later submission date. Short positions, full derivatives, and current intent are not disclosed.

How to Interpret the PYXS Fundamentals Score

PYXS rates 39/100 on our five-factor fundamentals screen, which puts it in the "Caution" band. The band name describes a fixed range in this model; it is not a recommendation or prediction. The calculation above shows how each reported input affected the result.

39/100 · Caution band

Pyxis Oncology, Inc. falls short on several of the measures we weight most heavily. Specifically: net margin (0.0%), return on equity (-179.1%). A low score reflects reported fundamentals only — it says nothing about the share price or about turnarounds already underway but not yet in the filings.

PYXS Fundamental Factors to Monitor

This is a review of reported fundamentals, not a price target or an estimate of future returns. These are the current figures that may be useful to monitor as new filings become available.

Lower current reading: The score is weighed down by net margin (0.0%) and return on equity (-179.1%). Changes in those reported figures, rather than share-price movement, would change this screen.

Positive Fundamental Inputs for PYXS

These are the Pyxis Oncology, Inc. figures that push the score up, taken straight from the most recent reported financials:

  • Gross Margin (78.4%)

Negative Fundamental Inputs & Risks for PYXS

These are the figures working against PYXS in the same model:

  • Net Margin (0.0%)
  • Return on Equity (-179.1%)
  • Debt/Equity (1.56)

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See how the metrics on this PYXS page — quality score, valuation, DCF scenarios, confidence labels, and data limitations — are organized in the downloadable research report.

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Guides to the specific measures used in this PYXS analysis:

Fundamental Analysis Guide

How the financial statements behind this page fit together.

Return on Equity (ROE)

Why PYXS's -179.1% return on equity matters for stock selection.

Stock Valuation Methods

How DCF, multiples and asset-based approaches value a company like Pyxis Oncology, Inc..

DCF Assumptions and Limitations

What a discounted cash flow estimate for PYXS depends on, and where it breaks down.

How to Read an AI Stock Report

What each section of a PYXS report is for, and what it leaves out.

What Are Demand Zones?

The technical side we deliberately keep out of the PYXS score.

Related Tools for PYXS

Semiconductor Demand Zone Tracker PYXS Live Chart PYXS SEC Filing News Earnings Calendar Institutional Ownership Sector Scanner Average Down Calculator

PYXS SEC Filing News

Latest SEC filings for PYXS explained in plain English — insider buys/sells (Form 4), proposed sales (Form 144), material events (8-K), and quarterly & annual reports.

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View all PYXS SEC Filing News →

Frequently Asked Questions about PYXS

Support and resistance are technical levels, so they are not part of the fundamentals score. Our demand zones page tracks semiconductor stocks; coverage does not extend to every ticker. Use the chart tool to identify price levels for PYXS manually.

This PYXS analysis is for educational and informational purposes only and does not constitute financial advice. Figures come from third-party feeds and can be delayed, standardized, incomplete, or inaccurate; verify material facts in primary filings and identified sources. Past performance does not guarantee future results. Read our full disclaimer.